Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.43 |
| ▸ | CTSL | P07711 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6842101 | 1.00 | CTSK (0.43) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4321788 | 0.83 | CTSK (0.59) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4321792 | 0.83 | CTSK (0.59) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4557501 | 0.77 | CTSK (0.47) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4557499 | 0.77 | CTSK (0.47) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL4316121 | 0.75 | CTSK (0.61) | CTSKCTSLCTSSMMP1ADAM17 | |
| SCHEMBL13784236 | 0.75 | CTSK (0.61) | CTSKCTSLCTSSMMP1ADAM17 | |
| SCHEMBL4316126 | 0.75 | CTSK (0.61) | CTSKCTSLCTSSMMP1ADAM17 | |
| SCHEMBL6622168 | 0.75 | TAS1R3 (0.62) | CTSKCTSLCTSSTAS1R3TAS1R1 | |
| SCHEMBL6622312 | 0.66 | MMP1 (0.52) | CTSKCTSLCTSSTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044201-A1 | Protease inhibitors | GLAXOSMITHKLINE LLC | 2004-03-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044201-A1 | Protease inhibitors | CTSK, CTSE, CTSZ | CTSK 1/4885CTSL 11/4885CTSS 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.