Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.56 |
| ▸ | CTSL | P07711 | 19/20 | 0.56 |
| ▸ | CTSS | P25774 | 18/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4315123 | 0.81 | CTSK (0.58) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4315121 | 0.80 | CTSK (0.57) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL13784634 | 0.79 | CTSK (0.51) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6842089 | 0.79 | CTSK (0.66) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6843710 | 0.78 | CTSK (0.51) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4318828 | 0.77 | CTSK (0.70) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6744240 | 0.77 | CTSK (0.70) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6213043 | 0.77 | CTSL (0.49) | CTSLCTSB | |
| SCHEMBL5983017 | 0.76 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6213680 | 0.73 | CTSK (0.56) | CTSKCTSLCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |