Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 19/20 | 0.68 |
| ▸ | CTSL | P07711 | 14/20 | 0.68 |
| ▸ | CTSS | P25774 | 11/20 | 0.68 |
| ▸ | CTSB | P07858 | 5/20 | 0.59 |
| ▸ | CTSV | O60911 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837024 | 0.91 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7012115 | 0.91 | CTSK (0.66) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6841551 | 0.83 | CTSL (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6837074 | 0.83 | CTSL (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL14131739 | 0.83 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7449693 | 0.82 | CTSK (0.72) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842084 | 0.82 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6841339 | 0.82 | CTSK (0.58) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842321 | 0.81 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6836911 | 0.81 | CTSK (0.76) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |