Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.41 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.41 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784332 | 0.89 | HRH3 (0.40) | SOAT1MLNRHRH3SMN1; SMN2THRB | |
| SCHEMBL17966438 | 0.89 | HRH3 (0.40) | SOAT1MLNRHRH3SMN1; SMN2THRB | |
| SCHEMBL17867144 | 0.88 | KDM4E (0.43) | SOAT1KDM4EMLNRGHSRHRH3 | |
| SCHEMBL29885671 | 0.85 | PSMB11 (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL29717170 | 0.82 | KDM4E (0.47) | SOAT1KDM4EGHSR | |
| SCHEMBL6466586 | 0.82 | KDM4E (0.47) | SOAT1KDM4EGHSR | |
| SCHEMBL16500668 | 0.82 | KDM4E (0.47) | SOAT1KDM4EGHSR | |
| SCHEMBL13784334 | 0.81 | HDAC3 (0.45) | HRH3 | |
| SCHEMBL29822681 | 0.81 | MLNR (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL13637393 | 0.81 | KDM4E (0.39) | SOAT1KDM4EGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566765-B2 | Heterocyclic compounds containing a nine-membered carbon-nitrogen ring | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |