Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14264299 | 0.95 | THRA (0.52) | THRATHRB | |
| SCHEMBL14264320 | 0.89 | THRA (0.45) | THRATHRB | |
| SCHEMBL14264300 | 0.88 | THRA (0.52) | THRATHRB | |
| SCHEMBL14264317 | 0.86 | THRA (0.54) | THRATHRB | |
| SCHEMBL14264298 | 0.86 | THRA (0.55) | THRATHRB | |
| SCHEMBL14264322 | 0.85 | THRA (0.48) | THRATHRB | |
| SCHEMBL5041149 | 0.83 | THRA (0.56) | THRATHRB | |
| SCHEMBL5041614 | 0.81 | THRB (0.64) | THRATHRB | |
| SCHEMBL5038116 | 0.81 | THRB (0.72) | THRATHRB | |
| SCHEMBL14278505 | 0.80 | THRB (0.62) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080835-A1 | THYROMIMETRIC COMPOUNDS IN TREATMENT OF DISEASE RELATED TO SONIC HEDGEHOG SIGNALLING | KARO BIO AB (SE) | 2009-07-02 | — | — | WO | disclosed |
| US-7342127-B2 | Substituted anilide ligands for the thyroid receptor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-11 | — | — | US | disclosed |
| US-7342127-B2 | Substituted anilide ligands for the thyroid receptor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-03-11 | — | — | US | disclosed |