Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784592 | 0.92 | CA1 (0.41) | TSHRESR1ESR2THRBCA1 | |
| SCHEMBL10033534 | 0.86 | NPC1 (0.45) | TSHRESR1ESR2THRBTDP1 | |
| SCHEMBL13784554 | 0.86 | ALDH1A1 (0.49) | TSHRESR1ESR2CA1CA2 | |
| SCHEMBL13784593 | 0.81 | TSHR (0.47) | TSHRTHRATHRBCA1CA2 | |
| SCHEMBL9619637 | 0.81 | IDO1 (0.49) | TSHRL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL13784596 | 0.81 | ELANE (0.46) | TSHRESR1THRBTDP1ALDH1A1 | |
| SCHEMBL17027832 | 0.81 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL17027708 | 0.81 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL17027725 | 0.81 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL17027826 | 0.81 | ALDH1A1 (0.46) | CA1CA2ALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563917-B2 | Silicon compound and a production process for silicon compound | CHISSO CORPORATION (JP) | 2009-07-21 | — | — | US | disclosed |