Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.60 |
| ▸ | CTSL | P07711 | 17/20 | 0.60 |
| ▸ | CTSS | P25774 | 13/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.45 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13784618 | 1.00 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842254 | 0.90 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6842272 | 0.90 | CTSK (0.75) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7486011 | 0.78 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6841551 | 0.77 | CTSL (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6837074 | 0.77 | CTSL (0.57) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6837057 | 0.75 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL13784217 | 0.75 | CTSK (0.74) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4316613 | 0.74 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4310547 | 0.74 | CTSK (0.68) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |