Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | PREP | P48147 | 3/20 | 0.44 |
| ▸ | FAP | Q12884 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046070 | 0.88 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL1046072 | 0.88 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL8564779 | 0.85 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL8564777 | 0.85 | DPP4 (0.46) | DPP4PREPFAPDPP8DPP9 | |
| Hydrochloric Acid SCHEMBL11113477 | 0.83 | DPP4 (0.42) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29380104 | 0.83 | ACE (0.49) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29985759 | 0.83 | PREP (0.44) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29874508 | 0.83 | ACE (0.49) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL18619544 | 0.82 | DPP4 (0.43) | DPP4PREPFAPDPP8DPP9 | |
| SCHEMBL29349875 | 0.82 | DPP4 (0.43) | DPP4PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170953-A1 | INDENTIFICATION OF COMPOUNDS THAT INHIBIT REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | TRIPEP AB (SE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170953-A1 | INDENTIFICATION OF COMPOUNDS THAT INHIBIT REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | OGA, ENGASE, GALE | DPP4 320/4885PREP 21/4885FAP 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.