Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11964677 | 0.88 | MEN1 (0.64) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL12056753 | 0.84 | USP2 (0.57) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL11964672 | 0.83 | MEN1 (0.60) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL15488854 | 0.83 | MEN1 (0.57) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL18829081 | 0.83 | MEN1 (0.60) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL14013308 | 0.82 | MEN1 (0.60) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL27449932 | 0.82 | MEN1 (0.83) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL19269179 | 0.82 | MEN1 (0.69) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL14901855 | 0.82 | MEN1 (0.64) | MEN1BLMKMT2AUSP2POLB | |
| SCHEMBL18680527 | 0.81 | MEN1 (0.65) | MEN1BLMKMT2AUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170749-A1 | Novel Compounds Which Interact With PEA-15 | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170749-A1 | Novel Compounds Which Interact With PEA-15 | PEBP1, EPS15, PSTPIP2 | MEN1 3441/4885BLM 4802/4885KMT2A 4041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.