Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341913 | 0.93 | MAPT (0.50) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL4332253 | 0.92 | MAPT (0.46) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL4338293 | 0.91 | THRB (0.48) | MAPTSMN1; SMN2THRBNPC1NFKB1 | |
| SCHEMBL9722390 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722301 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722257 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722195 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722239 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722126 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A | |
| SCHEMBL9722295 | 0.91 | MAPT (0.68) | MAPTSMN1; SMN2THRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |