Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338293 | 0.93 | THRB (0.48) | MAPTSMN1; SMN2RARBTHRBNPC1 | |
| SCHEMBL13785245 | 0.92 | MAPT (0.57) | MAPTSMN1; SMN2THRBNPC1LMNA | |
| SCHEMBL16425791 | 0.90 | MAPT (0.53) | MAPTSMN1; SMN2RARBTHRBNPC1 | |
| SCHEMBL24764454 | 0.89 | NPC1 (0.49) | MAPTSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL14500157 | 0.89 | NPC1 (0.49) | MAPTSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL3192599 | 0.89 | NPC1 (0.49) | MAPTSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL13768006 | 0.88 | NPC1 (0.47) | MAPTSMN1; SMN2NPC1LMNANFKB1 | |
| SCHEMBL14302567 | 0.87 | PTPN11 (0.48) | MAPTSMN1; SMN2RARBNPC1LMNA | |
| SCHEMBL497301 | 0.87 | MAPT (0.47) | MAPTSMN1; SMN2THRBNPC1LMNA | |
| SCHEMBL7073546 | 0.87 | THRB (0.46) | MAPTSMN1; SMN2RARBTHRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2017-12-28 | — | — | US | disclosed |
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| EP-1169293-B1 | LIQUID CRYSTAL COMPOUNDS | ROLIC AG (CH) | 2009-07-22 | — | — | EP | disclosed |
| US-6733690-B1 | ACRYLIC ESTER POLYMERS | ROLIC AG (CH) | 2004-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | VIM, SMCHD1, SMC4 | MAPT 18/4885SMN1; SMN2 2562/4885RARB 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.