SCHEMBL13786199

SCHEMBL13786199

CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1cc(C)c(S(=O)(=O)N(C)CCC(=O)N=O)s1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VDR P11473 16/20 0.53
AR P10275 5/20 0.45
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3393186 0.91 VDR (0.55) VDRARHDAC3
SCHEMBL3393172 0.88 VDR (0.53) VDRARHDAC3
SCHEMBL13675096 0.86 VDR (0.50) VDRARHDAC3
SCHEMBL3395458 0.81 VDR (0.67) VDRARHDAC3
SCHEMBL3395616 0.81 VDR (0.67) VDRARHDAC3
SCHEMBL13366676 0.79 VDR (0.56) VDRARHDAC3
Acetic Acid SCHEMBL3395937 0.79 VDR (0.63) VDRARHDAC3
SCHEMBL3389828 0.78 VDR (0.57) VDRARHDAC3
SCHEMBL13786001 0.78 VDR (0.45) VDRAR
SCHEMBL13786200 0.77 VDR (0.53) VDRARHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1511740-B1 PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS LILLY CO ELI (US) 2009-07-08 EP disclosed