Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033506 | 0.76 | F10 (0.64) | F10 | |
| SCHEMBL4033502 | 0.76 | F10 (0.64) | F10 | |
| SCHEMBL17358324 | 0.75 | F10 (0.38) | ALDH1A1LMNACYP2D6F10HPGD | |
| SCHEMBL1379829 | 0.72 | F10 (0.63) | ALDH1A1LMNAMAPTL3MBTL1CYP2D6 | |
| SCHEMBL1379964 | 0.72 | CYP2D6 (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL4444789 | 0.70 | F10 (0.45) | LMNAMAPTMEN1KMT2AF10 | |
| SCHEMBL5428908 | 0.70 | F10 (0.60) | ALDH1A1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4448089 | 0.69 | F10 (0.46) | F10 | |
| SCHEMBL3469024 | 0.69 | CYP3A4 (0.67) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL8306979 | 0.68 | METAP2 (0.48) | ALDH1A1MAPTMEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |