Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180572 | 0.83 | MCHR1 (0.43) | KDM4EMCHR1NPSR1AAK1 | |
| SCHEMBL4033672 | 0.77 | F10 (0.63) | SMN1; SMN2 | |
| SCHEMBL1378701 | 0.72 | ALDH1A1 (0.46) | CYP2D6CYP2C9NPC1SMN1; SMN2KDM4E | |
| SCHEMBL1379829 | 0.71 | F10 (0.63) | CYP2D6CYP2C9L3MBTL1HPGDALDH1A1 | |
| SCHEMBL3236814 | 0.63 | KMT2A (0.65) | NPC1L3MBTL1HPGDMEN1KMT2A | |
| SCHEMBL3039450 | 0.63 | NPC1 (0.56) | CYP2D6CYP2C9NPC1SMN1; SMN2KDM4E | |
| SCHEMBL14886137 | 0.62 | MAPT (0.67) | SMN1; SMN2HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL29349031 | 0.62 | HPGD (0.71) | NPC1SMN1; SMN2L3MBTL1HPGDMEN1 | |
| SCHEMBL3037762 | 0.62 | L3MBTL1 (0.51) | CYP2D6CYP2C9NPC1SMN1; SMN2KDM4E | |
| SCHEMBL3674141 | 0.62 | CYP3A4 (0.75) | CYP2D6CYP2C9L3MBTL1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |