Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.76 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.76 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473185 | 1.00 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL7359174 | 0.87 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8476245 | 0.87 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7363153 | 0.87 | PDE4B (0.82) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8344453 | 0.87 | PDE4B (0.71) | PDE4APDE4BPDE4CPDE4DPOLB | |
| Cilomilast SCHEMBL26372 | 0.86 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D | |
| Cilomilast SCHEMBL13777301 | 0.86 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D | |
| Cilomilast SCHEMBL27515 | 0.86 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D | |
| Cilomilast SCHEMBL27516 | 0.86 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D | |
| Cilomilast SCHEMBL5975855 | 0.86 | PDE4B (1.00) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550133-B2 | Respiratory drug condensation aerosols and methods of making and using them | ALEXZA PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |