SCHEMBL13790959

SCHEMBL13790959

COC(=O)Oc1ccc(C[Si](C)(C)O[Si](C)(C)Cc2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 5/20 0.40
MAPT P10636 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
UTS2R Q9UKP6 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 2/20 0.38
HPGD P15428 2/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13986637 0.90 SMN1; SMN2 (0.45) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL13881846 0.86 KMT2A (0.42) KMT2ALMNAALDH1A1MAPTGAA
SCHEMBL13583206 0.85 LMNA (0.62) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL13318047 0.81 ELANE (0.51) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL1598492 0.80 LMNA (0.61) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL10249515 0.79 AGXT (0.43) ALDH1A1HTT
SCHEMBL13881842 0.77 MAPT (0.40) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL12451823 0.76 LMNA (0.48) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL14205190 0.76 LMNA (0.55) KMT2ALMNAALDH1A1MAPTHSD17B10
SCHEMBL676909 0.73 KMT2A (0.58) KMT2ALMNAALDH1A1MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7541125-B2 Organic photoconductor, manufacturing method thereof, and process cartridge and image formation apparatus using the same photoconductor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-06-02 US disclosed
US-7529504-B2 Organic photoconductor, process cartridge and image forming apparatus both employing the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-05-05 US disclosed
US-7466326-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-12-16 US disclosed
US-7378212-B2 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-05-27 US disclosed
US-20070019984-A1 Organic photoconductor, process cartridge and image forming apparatus both employing the same KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-25 US disclosed
US-20070003853-A1 Image forming method, photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-01-04 US disclosed