SCHEMBL10249515

SCHEMBL10249515

Cc1ccc(C[Si](C)(C)O[Si](C)(C)Cc2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.43
IDO1 P14902 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ACHE P22303 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESR1 P03372 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 1/20 0.36
PYCR1 P32322 1/20 0.35
KCNH2 Q12809 1/20 0.35
CHRNA7 P36544 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17225128 0.86 AGXT (0.41) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL10249537 0.85 HPGD (0.38) AGXTIDO1CYP1A2ALDH1A1KCNH2
SCHEMBL17791455 0.84 AGXT (0.39) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL6580864 0.79 ESR1 (0.64) IDO1TAAR1ACHEESR1CA2
SCHEMBL13790959 0.79 KMT2A (0.42) ALDH1A1HTT
SCHEMBL5388447 0.78 TSHR (0.42) IDO1CYP1A2TAAR1ALDH1A1
SCHEMBL19514749 0.78 AGXT (0.44) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL9231420 0.77 CYP1A2 (0.46) AGXTIDO1CYP1A2CYP2A6TAAR1
SCHEMBL9615514 0.77 IDO1 (0.50) AGXTIDO1TAAR1CA1CA2
SCHEMBL986310 0.77 ESR1 (0.61) AGXTIDO1CYP1A2CYP2A6TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9188887-B2 Polycarbonate copolymer, coating fluid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer IDEMITSU KOSAN CO., LTD. (JP) 2015-11-17 US disclosed
US-8519082-B2 Polycarbonate copolymer, coating liquid using same, and electrophotographic photosensitive body IDEMITSU KOSAN CO., LTD. (JP) 2013-08-27 US disclosed
US-20120100474-A1 POLYCARBONATE COPOLYMER, COATING LIQUID USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY IDEMITSU KOSAN CO., LTD. (JP) 2012-04-26 US disclosed