Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484632 | 0.78 | TDP1 (0.33) | TDP1 | |
| SCHEMBL25453253 | 0.78 | CA2 (0.35) | TDP1 | |
| SCHEMBL15592774 | 0.78 | CA2 (0.35) | TDP1 | |
| SCHEMBL14011640 | 0.78 | CA2 (0.35) | TDP1 | |
| SCHEMBL19361685 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL21844011 | 0.76 | CNR2 (0.32) | TDP1 | |
| SCHEMBL13792568 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL13707918 | 0.76 | CNR2 (0.32) | TDP1 | |
| SCHEMBL14130636 | 0.76 | TDP1 (0.32) | TDP1 | |
| SCHEMBL12401103 | 0.76 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550559-B2 | Acylsulfonamide compounds as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2009-06-23 | — | — | US | disclosed |
| US-7399749-B2 | Substituted prolines as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |