Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793062 | 0.89 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MEN1KMT2ASOAT1 | |
| SCHEMBL13793023 | 0.86 | KCNA5 (0.43) | NPBWR1ALDH1A1MEN1KMT2ASOAT1 | |
| SCHEMBL13792763 | 0.85 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1MEN1KMT2ASOAT1 | |
| SCHEMBL13792818 | 0.85 | TP53 (0.53) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13793156 | 0.85 | TNF (0.47) | L3MBTL1ALDH1A1MEN1KMT2ASOAT1 | |
| SCHEMBL13792166 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ACXCR4 | |
| SCHEMBL6361058 | 0.84 | PPARA (0.47) | L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL13793064 | 0.84 | CMA1 (0.47) | ALDH1A1MEN1KMT2ASOAT1CXCR4 | |
| SCHEMBL3996653 | 0.84 | CMA1 (0.47) | L3MBTL1ALDH1A1MEN1KMT2ACXCR4 | |
| SCHEMBL13792788 | 0.83 | CMA1 (0.44) | NPBWR1ALDH1A1MEN1KMT2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544812-B2 | For example, 2-(4-{2-[1-(4-tert-Butyl-benzyl)-3-methyl-2-oxo-imidazolidin-4-yl]-ethoxy}-2-methyl-phenoxy)-2-methyl-propionic acid, 2-(4-{3-[1-(4-tert-Butyl-benzyl)-3-methyl-2-oxo-imidazolidin-4-yl]-propyl}-2-methyl-phenoky)-2-methyl-propionic acid; for treating diabetes mellitus | ELI LILLY AND COMPANY (US) | 2009-06-09 | — | — | US | disclosed |
| US-7544812-B2 | For example, 2-(4-{2-[1-(4-tert-Butyl-benzyl)-3-methyl-2-oxo-imidazolidin-4-yl]-ethoxy}-2-methyl-phenoxy)-2-methyl-propionic acid, 2-(4-{3-[1-(4-tert-Butyl-benzyl)-3-methyl-2-oxo-imidazolidin-4-yl]-propyl}-2-methyl-phenoky)-2-methyl-propionic acid; for treating diabetes mellitus | ELI LILLY AND COMPANY (US) | 2009-06-09 | — | — | US | disclosed |