Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379346 | 0.86 | MEN1 (0.41) | KMT2APOLBMEN1 | |
| SCHEMBL1376532 | 0.85 | KMT2A (0.43) | KMT2AATMPOLBMEN1 | |
| SCHEMBL1379356 | 0.83 | ATM (0.39) | KMT2AATMGFERPOLBMEN1 | |
| SCHEMBL3161685 | 0.81 | KMT2A (0.41) | KMT2AATMGFERPOLB | |
| SCHEMBL4070565 | 0.80 | HTR7 (0.45) | KMT2AATMGFERPOLB | |
| SCHEMBL2920939 | 0.79 | KCNH2 (0.44) | — | |
| SCHEMBL4065150 | 0.78 | ATM (0.44) | KMT2AATMGFERPOLB | |
| SCHEMBL4069110 | 0.78 | HTR7 (0.43) | KMT2AATMGFERPOLB | |
| SCHEMBL4065505 | 0.78 | KMT2A (0.42) | KMT2AATMGFERPOLB | |
| Hydrochloric Acid SCHEMBL4064063 | 0.77 | HTR7 (0.43) | KMT2AATMGFERPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4654035-B2 | — | — | 2011-03-16 | — | — | JP | claimed |
| EP-1560488-B1 | ANTIBACTERIAL AGENTS | GLAXO GROUP LTD (GB) | 2010-09-01 | — | — | EP | claimed |