Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379484 | 0.81 | KMT2A (0.53) | KMT2AATMGFERPOLB | |
| SCHEMBL4070565 | 0.79 | HTR7 (0.45) | KMT2AATMGFERHTR7HTR6 | |
| SCHEMBL4720275 | 0.79 | CCR8 (0.41) | KMT2AATMGFER | |
| SCHEMBL4717181 | 0.79 | CCR8 (0.41) | KMT2AATMGFER | |
| SCHEMBL4069110 | 0.77 | HTR7 (0.43) | KMT2AATMGFERHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL4064063 | 0.76 | HTR7 (0.43) | KMT2AATMGFERHTR7HTR6 | |
| SCHEMBL4065150 | 0.76 | ATM (0.44) | KMT2AATMGFERPOLB | |
| SCHEMBL4065505 | 0.75 | KMT2A (0.42) | KMT2AATMGFERPOLB | |
| SCHEMBL3171788 | 0.74 | KMT2A (0.41) | KMT2AATMGFERPOLB | |
| SCHEMBL3162871 | 0.73 | ATM (0.41) | KMT2AATMGFERPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560821-B1 | ANTIBACTERIAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-03-24 | — | — | EP | claimed |
| EP-1560821-B1 | ANTIBACTERIAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2010-03-24 | — | — | EP | disclosed |
| US-7232832-B2 | Antibacterial agents | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7232832-B2 | Antibacterial agents | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |