Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 13/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796453 | 0.78 | MCHR1 (0.55) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794892 | 0.77 | ALDH1A1 (0.47) | MCHR1ADRA2ANPY5RCYP1A2CYP2D6 | |
| SCHEMBL14606606 | 0.74 | PDE10A (0.51) | MCHR1ADRA2ANPY5RPDE10ACYP1A2 | |
| SCHEMBL13794498 | 0.74 | MCHR1 (0.52) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL14606873 | 0.73 | PDE10A (0.49) | MCHR1ADRA2ANPY5RPDE10ACYP1A2 | |
| SCHEMBL13796088 | 0.72 | MCHR1 (0.42) | MCHR1ADRA2ANPY5RPDE10ACYP1A2 | |
| SCHEMBL13808297 | 0.70 | CYP1A2 (0.41) | MCHR1ADRA2ANPY5RPDE10ACYP1A2 | |
| SCHEMBL13795179 | 0.69 | MCHR1 (0.54) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13797329 | 0.68 | MCHR1 (0.54) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795328 | 0.68 | MCHR1 (0.55) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |