Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13144970 | 1.00 | MAPT (0.57) | MAPTBCHEACHEBACE1LMNA | |
| SCHEMBL13805766 | 0.83 | BCHE (0.56) | MAPTBCHEACHEBACE1LMNA | |
| SCHEMBL3543089 | 0.78 | MAPT (0.63) | MAPTMEN1KMT2ANAMPTPOLB | |
| SCHEMBL3543093 | 0.78 | MAPT (0.63) | MAPTMEN1KMT2ANAMPTPOLB | |
| SCHEMBL30441578 | 0.75 | ERN1 (0.44) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL13245958 | 0.75 | MAPT (0.59) | MAPTMEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL2993765 | 0.75 | MAPT (0.62) | MAPTMEN1KMT2ANAMPTPOLB | |
| SCHEMBL13245959 | 0.75 | MAPT (0.62) | MAPTMEN1KMT2ANAMPTPOLB | |
| SCHEMBL2984932 | 0.75 | MAPT (0.59) | MAPTMEN1KMT2ANAMPTALDH1A1 | |
| SCHEMBL3544325 | 0.74 | MAPT (0.58) | MAPTMEN1KMT2ANAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547800-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-7547800-B2 | Process for trans-4-amino-1-cyclohexanecarboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| US-7459580-B2 | Process for trans-4-amino-1-cyclohexanecarboxilic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-7459580-B2 | Process for trans-4-amino-1-cyclohexanecarboxilic acid derivatives | SHIONOGI & CO., LTD. (JP) | 2008-12-02 | — | — | US | disclosed |
| US-20080039662-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXILIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| US-20080039662-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXILIC ACID DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| US-7314950-B2 | Process for producing trans-4-amino-1-cyclohexanecarboxilic acid derivative | SHIONOGI & CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043094-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVES | ACMSD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, AADAT | MAPT 1721/4885BCHE 2148/4885ACHE 2838/4885 |
| US-20080039662-A1 | PROCESS FOR TRANS-4-AMINO-1-CYCLOHEXANECARBOXILIC ACID DERIVATIVES | AADAT, ACMSD, AAAS | MAPT 1445/4885BCHE 1354/4885ACHE 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.