SCHEMBL13795553

CCOC(=O)N1CCN(C(=O)C(Cc2cccc(N/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)c2)NS(=O)(=O)c2c(C(C)C)cc(C(C)C)cc2C(C)C)CC1

nearest known ligand 0.64

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	PLAU	P00749	19/20	0.64

▸	PLAT	P00750	4/20	0.64

▸	PLG	P00747	15/20	0.61

▸	F10	P00742	7/20	0.61

▸	F2	P00734	6/20	0.61

▸	ST14	Q9Y5Y6	6/20	0.61

▸	HPN	P05981	2/20	0.61

▸	KLKB1	P03952	1/20	0.61

▸	TPSG1	Q9NRR2	1/20	0.61

▸	HGFAC	Q04756	1/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13866547	0.82	PLAU (0.41)	PLAUPLATPLGF10F2
SCHEMBL13727903	0.80	PLAU (0.84)	PLAUPLATPLGF10F2
SCHEMBL437042	0.77	PLAU (0.90)	PLAUPLATPLGF10F2
SCHEMBL13866917	0.77	PLAU (0.78)	PLAUPLATPLGF10F2
SCHEMBL12618903	0.77	PLAU (0.78)	PLAUPLATPLGF10F2
Upamostat SCHEMBL31331918	0.76	PLAU (1.00)	PLAUPLATPLGF10F2
Upamostat SCHEMBL29376462	0.76	PLAU (1.00)	PLAUPLATPLGF10F2
Upamostat SCHEMBL437037	0.76	PLAU (1.00)	PLAUPLATPLGF10F2
Upamostat SCHEMBL20669283	0.76	PLAU (1.00)	PLAUPLATPLGF10F2
SCHEMBL20675070	0.76	PLAU (1.00)	PLAUPLATPLGF10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1511721-B1	GUANIDINO PHENYLALANIN COMPOUNDS USED AS UROKINASE INHIBITORS	WILEX AG (DE)	2009-07-01	—	—	EP	disclosed