Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 4/20 | 0.41 |
| ▸ | PLAT | P00750 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795553 | 0.82 | PLAU (0.64) | PLAUPLGF2F10ST14 | |
| SCHEMBL207904 | 0.76 | PDK1 (0.47) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12891391 | 0.74 | LTA4H (0.42) | — | |
| SCHEMBL316880 | 0.72 | LMNA (0.50) | ALDH1A1LMNASLC7A5SMN1; SMN2CYP1A2 | |
| SCHEMBL316881 | 0.72 | LMNA (0.50) | ALDH1A1LMNASLC7A5SMN1; SMN2CYP1A2 | |
| SCHEMBL20057655 | 0.71 | CYP17A1 (0.39) | ALDH1A1 | |
| SCHEMBL17569733 | 0.71 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19275814 | 0.71 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2908042 | 0.71 | TSHR (0.63) | PLAUMAPTALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL30337959 | 0.71 | TSHR (0.63) | PLAUMAPTALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538216-B2 | Guanidino phenylalanin compounds used as urokinase inhibitors | WILEX AG (DE) | 2009-05-26 | — | — | US | disclosed |