Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 13/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.62 |
| ▸ | AQP1 | P29972 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | NPY1R | P25929 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NPY2R | P49146 | 1/20 | 0.62 |
| ▸ | NPY4R | P50391 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795833 | 0.90 | NPY5R (0.52) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796737 | 0.89 | NPY5R (0.65) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796889 | 0.88 | NPY5R (0.49) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13795622 | 0.88 | NPY5R (0.64) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796342 | 0.87 | NPY5R (0.57) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796842 | 0.87 | AQP1 (0.47) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13795942 | 0.87 | NPY5R (0.68) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796090 | 0.86 | NPY5R (0.51) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL13796330 | 0.86 | MRGPRX1 (0.58) | NPY5RADRA2AMCHR1AQP1ALDH1A1 | |
| SCHEMBL14606892 | 0.86 | MRGPRX1 (0.51) | NPY5RADRA2AMCHR1AQP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |