Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 2/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 14/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | NPY4R | P50391 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796973 | 0.94 | AQP1 (0.66) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13797021 | 0.90 | NPY5R (0.70) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796987 | 0.90 | NPY5R (0.58) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13795925 | 0.88 | NPY5R (0.57) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796982 | 0.88 | AQP1 (0.51) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13797015 | 0.88 | NPY5R (0.55) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13797014 | 0.87 | NPY5R (0.54) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13795948 | 0.87 | AQP1 (0.69) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796980 | 0.87 | NPY5R (0.54) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13795923 | 0.86 | NPY5R (0.56) | AQP1NPY5RADRA2AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |