Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 2/20 | 0.66 |
| ▸ | NPY5R | Q15761 | 15/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | NPY4R | P50391 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796460 | 0.94 | AQP1 (0.63) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796449 | 0.90 | NPY5R (0.74) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796443 | 0.90 | NPY5R (0.60) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13795948 | 0.90 | AQP1 (0.69) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796529 | 0.88 | AQP1 (0.66) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796446 | 0.88 | NPY5R (0.60) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13797006 | 0.87 | AQP1 (0.53) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796976 | 0.87 | NPY5R (0.58) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796949 | 0.87 | AQP1 (0.65) | AQP1NPY5RADRA2AMCHR1ALDH1A1 | |
| SCHEMBL13796975 | 0.86 | NPY5R (0.57) | AQP1NPY5RADRA2AMCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |