Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796670 | 0.90 | PGR (0.50) | PGRSLC6A4NR3C1ADORA3SLC6A2 | |
| SCHEMBL13797684 | 0.75 | PGR (0.49) | PGRSLC6A4NR3C1ARLMNA | |
| SCHEMBL13556635 | 0.75 | PGR (0.42) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| SCHEMBL13556649 | 0.74 | AR (0.50) | PGRSLC6A4NR3C1PDE4DAR | |
| SCHEMBL13768994 | 0.74 | PGR (0.60) | PGRSLC6A4NR3C1ARLMNA | |
| SCHEMBL12998932 | 0.74 | PGR (0.60) | PGRSLC6A4NR3C1ARLMNA | |
| SCHEMBL12942766 | 0.73 | PGR (0.42) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| SCHEMBL15417491 | 0.72 | PGR (0.52) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| SCHEMBL13556638 | 0.72 | AR (0.35) | PGRARNR3C2 | |
| SCHEMBL13770167 | 0.71 | PGR (0.55) | PGRSLC6A4NR3C1NR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083269-A1 | 15,16-METHYLENE-17-HYDROXY-19-NOR-21-CARBOXYLIC ACID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |