Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606663 | 0.85 | GBA1 (0.56) | GBA1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13796481 | 0.84 | NPY5R (0.62) | GBA1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13795998 | 0.76 | NPY5R (0.51) | GBA1F2NPY5RNPY1R | |
| SCHEMBL13796785 | 0.76 | GBA1 (0.47) | GBA1NPY5RNPY1R | |
| SCHEMBL13797033 | 0.76 | GBA1 (0.47) | GBA1NPY5RNPY1R | |
| SCHEMBL7973287 | 0.75 | NPY5R (0.48) | GBA1NSD2EPHX2NPY5RHTR4 | |
| SCHEMBL10677948 | 0.74 | F2 (0.62) | GBA1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL13713919 | 0.74 | F2 (0.62) | F2PRSS1PRSS2PRSS3NSD2 | |
| SCHEMBL13794173 | 0.73 | NPY5R (0.71) | GBA1NSD2NPY5RNPY1R | |
| SCHEMBL13796004 | 0.73 | NPY1R (0.62) | NPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |