Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960086 | 0.81 | NPY5R (0.56) | NPY5RPOLBNPSR1 | |
| SCHEMBL7971400 | 0.79 | NPY5R (0.72) | NPY5RGBA1POLB | |
| SCHEMBL14606663 | 0.78 | GBA1 (0.56) | NPY5RGBA1HDAC4HDAC10HDAC6 | |
| SCHEMBL13797012 | 0.75 | GBA1 (0.54) | NPY5RGBA1HDAC4HDAC10HDAC6 | |
| SCHEMBL30632892 | 0.75 | EPHX2 (0.59) | GBA1HDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL3851599 | 0.74 | NPY5R (0.68) | NPY5RGBA1POLB | |
| SCHEMBL7960267 | 0.73 | HDAC3 (0.73) | NPY5RHDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL29877086 | 0.73 | HDAC3 (0.73) | NPY5RHDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL8890437 | 0.73 | NPY5R (0.63) | NPY5RHDAC4HDAC10HDAC6HDAC5 | |
| SCHEMBL13794173 | 0.72 | NPY5R (0.71) | NPY5RGBA1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |