Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797345 | 0.85 | PGR (0.48) | PGRARNR3C2CYP19A1 | |
| SCHEMBL13770651 | 0.78 | PGR (0.49) | PGRARNR3C2CYP19A1 | |
| SCHEMBL13796510 | 0.72 | PGR (0.47) | PGRARNR3C2CYP19A1 | |
| SCHEMBL13770481 | 0.72 | AR (0.41) | PGRARNR3C2CYP19A1 | |
| SCHEMBL16564394 | 0.64 | PGR (0.53) | PGRARNR3C2CYP19A1 | |
| SCHEMBL16564406 | 0.64 | PGR (0.53) | PGRARNR3C2CYP19A1 | |
| SCHEMBL13925594 | 0.64 | PGR (0.51) | PGRARNR3C2CYP19A1 | |
| SCHEMBL13770129 | 0.64 | AR (0.46) | PGRARNR3C2 | |
| SCHEMBL13770653 | 0.64 | AR (0.48) | PGRARNR3C2 | |
| SCHEMBL10089114 | 0.64 | PGR (0.57) | PGRARNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |