Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 14/20 | 0.53 |
| ▸ | AR | P10275 | 13/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564394 | 1.00 | PGR (0.53) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL3768624 | 0.89 | PGR (0.54) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL3763967 | 0.89 | PGR (0.54) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564430 | 0.88 | PGR (0.63) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564562 | 0.88 | PGR (0.63) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564405 | 0.84 | PGR (0.52) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564563 | 0.82 | PGR (0.49) | PGRARNR3C2LMNASLC6A4 | |
| SCHEMBL16564580 | 0.82 | PGR (0.37) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16564558 | 0.79 | AR (0.49) | PGRARNR3C2LMNASLC6A4 | |
| SCHEMBL16564338 | 0.79 | AR (0.49) | PGRARNR3C2LMNASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238149-B1 | 19-NOR-STEROID DERIVATIVES WITH A 15ALPHA, 16ALPHA-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | claimed |
| EP-2238149-B1 | 19-NOR-STEROID DERIVATIVES WITH A 15ALPHA, 16ALPHA-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | disclosed |