Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.45 |
| ▸ | SHBG | P04278 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797501 | 0.76 | PGR (0.59) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13797684 | 0.73 | PGR (0.49) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13474783 | 0.72 | PGR (0.57) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13770462 | 0.72 | PGR (0.57) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13055680 | 0.71 | ALDH1A1 (0.65) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL4213527 | 0.71 | ALDH1A1 (0.65) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13797495 | 0.71 | AR (0.44) | PGRAR | |
| SCHEMBL13770151 | 0.69 | PGR (0.59) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL3643471 | 0.69 | CYP19A1 (0.62) | CYP19A1PGRARSERPINA6SHBG | |
| SCHEMBL13372732 | 0.69 | CYP19A1 (0.62) | CYP19A1PGRARSERPINA6SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |