Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 6/20 | 0.46 |
| ▸ | TNFSF11 | O14788 | 4/20 | 0.44 |
| ▸ | HTR6 | P50406 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793681 | 0.80 | MCHR1 (0.64) | PLK1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8999103 | 0.79 | PLK1 (0.74) | PLK1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13793906 | 0.77 | MCHR1 (0.57) | PLK1TNFSF11 | |
| SCHEMBL13797657 | 0.72 | DGAT1 (0.54) | LMNASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL13797659 | 0.72 | MEN1 (0.62) | LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL3947644 | 0.71 | TP53 (0.51) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8999130 | 0.71 | PLK1 (1.00) | PLK1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL937937 | 0.71 | NPY5R (0.60) | LMNASMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL13796619 | 0.71 | CTNNB1 (0.52) | LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL13797643 | 0.70 | MAPT (0.50) | LMNASMN1; SMN2MEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |