Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ESRRG | P62508 | 6/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797648 | 0.89 | NPC1 (0.56) | RXFP1NPC1RAB9APPARGNCOA2 | |
| SCHEMBL13797641 | 0.80 | MEN1 (0.50) | RXFP1NPC1RAB9ATP53MAPT | |
| SCHEMBL13797658 | 0.79 | TDP1 (0.60) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL13796619 | 0.77 | CTNNB1 (0.52) | RXFP1NPC1RAB9ATP53MAPT | |
| SCHEMBL13797659 | 0.77 | MEN1 (0.62) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13797645 | 0.77 | KDM4E (0.51) | NPC1RAB9ATP53MAPTKDM4E | |
| SCHEMBL13797657 | 0.77 | DGAT1 (0.54) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL13797655 | 0.76 | PLAU (0.57) | NPC1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3947644 | 0.76 | TP53 (0.51) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL13797656 | 0.75 | ADORA3 (0.54) | NPC1RAB9ATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |