Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.60 |
| ▸ | LYN | P07948 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359141 | 0.88 | LYN (0.45) | MAPK14LYNMAPK9ALDH1A1MEN1 | |
| SCHEMBL13797936 | 0.85 | MAPK14 (0.68) | MAPK14LYNMAPK9ALDH1A1MEN1 | |
| SCHEMBL13359288 | 0.84 | MAPK14 (0.65) | MAPK14LYNMAPK9ALDH1A1MEN1 | |
| SCHEMBL13797996 | 0.84 | MAPK14 (0.69) | MAPK14LYNMAPK9 | |
| SCHEMBL13797943 | 0.84 | MAPK14 (0.72) | MAPK14LYNMAPK9 | |
| SCHEMBL13797938 | 0.83 | MAPK14 (0.73) | MAPK14LYNMAPK9 | |
| SCHEMBL13797952 | 0.82 | MAPK14 (0.72) | MAPK14LYNMAPK9ALDH1A1MEN1 | |
| SCHEMBL13359242 | 0.81 | MAPK14 (0.68) | MAPK14LYNMAPK9 | |
| SCHEMBL13797962 | 0.80 | MAPK14 (0.67) | MAPK14LYNMAPK9POLB | |
| SCHEMBL13797993 | 0.80 | MAPK14 (0.74) | MAPK14LYNMAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550461-B2 | Benzofuran and benzothiophene compounds useful in treating cytokine mediated diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550461-B2 | Benzofuran and benzothiophene compounds useful in treating cytokine mediated diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |