Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LYN | P07948 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797966 | 0.88 | MAPK14 (0.60) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359286 | 0.85 | MAPK14 (0.49) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359241 | 0.80 | LYN (0.55) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359212 | 0.79 | LYN (0.51) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359264 | 0.78 | LYN (0.59) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359211 | 0.74 | MAPK14 (0.40) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13797936 | 0.72 | MAPK14 (0.68) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13359288 | 0.71 | MAPK14 (0.65) | LYNMAPK9MAPK14MEN1KMT2A | |
| SCHEMBL13797996 | 0.71 | MAPK14 (0.69) | LYNMAPK9MAPK14 | |
| SCHEMBL13797943 | 0.70 | MAPK14 (0.72) | LYNMAPK9MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497278-B1 | HETEROCYCLIC AMIDE DERIVATIVES AS CYTOKINE INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2010-05-26 | — | — | EP | disclosed |