Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850225 | 0.91 | EPHX2 (0.37) | EPHX2CYP2C9CYP2J2CXCR2OPRD1 | |
| SCHEMBL14269 | 0.86 | CXCR2 (0.41) | EPHX2CXCR2POLBP2RY1 | |
| SCHEMBL17485862 | 0.85 | EGFR (0.36) | EPHX2CYP2C9CYP2J2CXCR2OPRD1 | |
| SCHEMBL13684 | 0.85 | EGFR (0.36) | EPHX2CYP2C9CYP2J2CXCR2OPRD1 | |
| SCHEMBL14268 | 0.81 | SIGMAR1 (0.37) | EPHX2POLB | |
| SCHEMBL17354488 | 0.80 | POLB (0.39) | MEN1KMT2APOLB | |
| SCHEMBL13604 | 0.78 | DPP4 (0.38) | EPHX2CYP2C9CYP2J2CXCR2P2RY1 | |
| SCHEMBL13857 | 0.78 | ALDH1A1 (0.38) | EPHX2KMT2A | |
| SCHEMBL17354223 | 0.77 | EPHX2 (0.43) | EPHX2MEN1KMT2A | |
| SCHEMBL13689 | 0.76 | CXCR2 (0.41) | EPHX2CXCR2POLBP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047323-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |