Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4106690 | 0.90 | L3MBTL1 (0.43) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL3838724 | 0.76 | ABCG2 (0.35) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL3838720 | 0.76 | ABCG2 (0.35) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL10195625 | 0.72 | L3MBTL1 (0.55) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL3819235 | 0.71 | CYP2C9 (0.58) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL13798730 | 0.71 | L3MBTL1 (0.53) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL9726900 | 0.70 | MERTK (0.51) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL12715754 | 0.70 | DHODH (0.39) | ABCG2CYP2C9CYP2C19ABCC3ESR1 | |
| SCHEMBL13798731 | 0.70 | CYP2C9 (0.38) | L3MBTL1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL12715758 | 0.69 | TTK (0.41) | ABCG2CYP2C9CYP2C19ABCC3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079412-A2 | REVERSE TRANSCRIPTASE INHIBITORS | ARDEA BIOSCIENCES INC. (US) | 2009-06-25 | — | — | WO | disclosed |