Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726830 | 0.79 | ABCG2 (0.49) | L3MBTL1LMNAGAAKMT2ASMN1; SMN2 | |
| SCHEMBL25004693 | 0.77 | MAPT (0.46) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL1625301 | 0.77 | MAPT (0.46) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL25003640 | 0.76 | MAPT (0.45) | MAPTL3MBTL1LMNATDP1GAA | |
| Hydrochloric Acid SCHEMBL23089681 | 0.76 | MAPT (0.45) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL7020732 | 0.75 | MAPT (0.49) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL29280753 | 0.73 | MAPT (0.45) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL31026401 | 0.72 | MAPT (0.45) | MAPTL3MBTL1LMNATDP1GAA | |
| SCHEMBL10195625 | 0.72 | L3MBTL1 (0.55) | MAPTL3MBTL1LMNATDP1KMT2A | |
| SCHEMBL12877828 | 0.72 | LMNA (0.46) | MAPTL3MBTL1LMNATDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032648-C | Process for preparation of platelet activating factor antagonist | FIZER LTD (GB) | 1996-08-28 | — | — | CN | disclosed |
| US-5149814-A | Alkyl 2-benzylidene-4-(2-alkylimidazopyrid-1-yl) benzoylacetate esters as intermediate compounds | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-5120747-A | Antiallergens, antiinflammatory agent | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5070205-A | Chemical intermediate for anticoagulants | PFIZER INC. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0310386-B1 | 4-ARYL-5-CARBAMOYL-1,4-DIHYDROPYRIDINES | Pfizer Limited (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-5063237-A | Antiallergens and antiinflammatory agents | PFIZER INC. (US) | 1991-11-05 | — | — | US | disclosed |
| US-4963560-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4935430-A | Platelet activating factor antagonists | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0365140-A1 | 1,4-Dihydropyridine derivatives | Pfizer Limited (GB) | 1990-04-25 | — | — | EP | disclosed |
| CN-1032439-A | A kind of preparation method of platelet-activating factor antagonist | PFIZER LTD (GB) | 1989-04-19 | — | — | CN | disclosed |
| EP-0310386-A2 | 4-Aryl-5-carbamoyl-1,4-dihydropyridines | Pfizer Limited (GB) | 1989-04-05 | — | — | EP | disclosed |