SCHEMBL137992

SCHEMBL137992

NCc1ccc(Cl)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28045785 0.98 GAA (0.48)
Hydrochloric Acid SCHEMBL5013501 0.98 GAA (0.48)
Hydrochloric Acid SCHEMBL3346503 0.98 GAA (0.48)
Acetonitrile SCHEMBL9525113 0.88 ALDH1A1 (0.47)
Isopropyl Alcohol SCHEMBL29044529 0.88 ALDH1A1 (0.47)
SCHEMBL5013443 0.85 ALDH1A1 (0.49)
SCHEMBL5008269 0.85 ALDH1A1 (0.49)
SCHEMBL165097 0.82 TAAR1 (0.52)
Hydrochloric Acid SCHEMBL14157130 0.80 TAAR1 (0.50)
SCHEMBL8196044 0.79 CYP2A6 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912457-A Pyrimidine triazole compound as well as preparation method and application thereof 郑州大学 2025-05-02 CN claimed
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN claimed
CN-116528599-B Multi-tooth ligand modified perovskite solar cell and preparation method thereof 长江三峡集团实业发展(北京)有限公司 2025-01-24 CN claimed
CN-116528599-A Multi-tooth ligand modified perovskite solar cell and preparation method thereof 长江三峡集团实业发展(北京)有限公司 2023-08-01 CN claimed
CN-116239517-A All-organic perovskite material and preparation method thereof 南方科技大学 2023-06-09 CN claimed
US-9884814-B2 Acylguanidines for treating osteoarthritis MERCK PATENT GMBH (DE) 2018-02-06 US claimed
US-9737875-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-08-22 US claimed
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 CN claimed
CN-105837500-A Synthetic method for N-(2-(3-(trifluoromethyl)phenoxy)-4-pyridyl)methylenimine 常州大学 2016-08-10 CN claimed
US-20150361037-A1 ACYLGUANIDINES FOR TREATING OSTEOARTHRITIS MERCK PATENT GMBH (DE) 2015-12-17 US claimed
EP-0609811-A1 Process for preparing 2-chloro-5-aminomethyl-pyridine KOEI CHEMICAL CO., Ltd. (JP) 1994-08-10 EP claimed
EP-0391205-B1 Process for the preparation of 2-chloro-5-aminomethyl-pyridine BAYER AG (DE) 1994-05-25 EP claimed
CN-1085213-A The preparation method of 2-chloro-5-aminomethyl-pyridine BAYER AG (DE) 1994-04-13 CN claimed
EP-0579970-A2 Process for the production of 2-chloro-5-aminomethylpyridine BAYER AG (DE) 1994-01-26 EP claimed
CN-1075958-A Process for preparing 2-chloro-5-alkylaminomethylpyridines BAYER AG (DE) 1993-09-08 CN claimed
EP-0556684-A1 Process for the preparation of 2-chloro-5-alkylamino-methylpyridines BAYER AG (DE) 1993-08-25 EP claimed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP claimed
EP-0474057-A1 Process for the preparation of N-(2-chloro-pyridine-5-yl-methyl)-ethylendiamin BAYER AG (DE) 1992-03-11 EP claimed
US-5026864-A Preparation of 2-chloro-5-aminomethyl-pyridine BAYER AKTIENGESELLSCHAFT (DE) 1991-06-25 US claimed
EP-0391205-A1 Process for the preparation of 2-chloro-5-aminomethyl-pyridine BAYER AG (DE) 1990-10-10 EP claimed