Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14157130 | 0.98 | TAAR1 (0.50) | TAAR1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL8196044 | 0.88 | CYP2A6 (0.48) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL19797822 | 0.83 | GAA (0.47) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL137992 | 0.82 | — | — | |
| SCHEMBL10483901 | 0.81 | SIGMAR1 (0.56) | KDM4EGAAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5013501 | 0.80 | GAA (0.48) | KDM4EGAAMAPTL3MBTL1CHRNA7 | |
| SCHEMBL10483958 | 0.80 | GAA (0.48) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3346503 | 0.80 | GAA (0.48) | KDM4EGAAMAPTL3MBTL1CHRNA7 | |
| Hydrochloric Acid SCHEMBL28045785 | 0.80 | GAA (0.48) | KDM4EGAAMAPTL3MBTL1CHRNA7 | |
| SCHEMBL10483903 | 0.79 | SIGMAR1 (0.49) | KDM4EGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | claimed |
| CN-106699646-A | Synthetic method of acetamiprid | 江苏长青生物科技有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-118265702-A | Microbiocidal isonicotinamide derivatives | 先正达农作物保护股份公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023166067-A1 | MICROBIOCIDAL PYRIDAZINONE AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023118011-A1 | MICROBIOCIDAL AZA-HETEROBIARYL DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023089049-A2 | MICROBIOCIDAL ISONICOTINIC AMIDE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2023-05-25 | — | — | WO | disclosed |
| US-20200392126-A1 | ISOXAZOLYL COMPOUNDS AS RECEPTOR MODULATING COMPOUNDS AND METHODS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2020-12-17 | — | — | US | disclosed |
| WO-2019109132-A1 | ISOXAZOLYL COMPOUNDS AS RECEPTOR MODULATING COMPOUNDS AND METHODS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2019-06-13 | — | — | WO | disclosed |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-9717242-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide for control of agricultural/horticultural pests | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| WO-2008144222-A2 | TRIAZOLYL AMINOPYRIMIDINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008079346-A1 | 5-CYAN0-4- (PYRROLO [2, 3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008076705-A1 | IMIDAZOLIDINONYL AMINOPYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER | ELI LILLY AND COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080033020-A1 | 3-Pyridinylethylbenzamide Derivatives as Fungicides | BAYER CROPSCIENCE S.A. (FR) | 2008-02-07 | — | — | US | disclosed |
| EP-1773776-A1 | 3-PYRIDINYLETHYLBENZAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006008191-A1 | 3-PYRIDINYLETHYLBENZAMIDE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-01-26 | — | — | WO | disclosed |
| US-4410530-A | CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| US-4195090-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
| US-4115575-A | CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033020-A1 | 3-Pyridinylethylbenzamide Derivatives as Fungicides | CYP1A2, CYP4B1, CYP4F2 | TAAR1 3735/4885KDM4E 1303/4885GAA 122/4885 |
| US-20200392126-A1 | ISOXAZOLYL COMPOUNDS AS RECEPTOR MODULATING COMPOUNDS AND METHODS AND USES THEREOF | CHRNA7, CHRNA5, CHRNA1 | TAAR1 321/4885KDM4E 2639/4885GAA 1391/4885 |
| US-10085449-B2 | N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests | NR2E1, CROCC, PRMT1 | TAAR1 72/4885KDM4E 95/4885GAA 4426/4885 |
| US-20170360041-A1 | N-[1-((6-CHLOROPYRIDIN-3-YL)METHYL)PYRIDIN-2(1H)-YLIDENE]-2,2,2- TRIFLUOROACETAMIDE FOR CONTROL OF AGRICULTURAL/HORTICULTURAL PESTS | NR2E1, CROCC, PRMT1 | TAAR1 72/4885KDM4E 95/4885GAA 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.