Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 16/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11757679 | 0.91 | ADRB2 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL11670126 | 0.82 | ADRB2 (0.57) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9768153 | 0.80 | ADRB2 (0.61) | ADRB3ADRB2ADRB1DRD2DRD1 | |
| SCHEMBL3220388 | 0.80 | ADRB2 (0.61) | ADRB3ADRB2ADRB1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL11750674 | 0.80 | ADRB2 (0.56) | ADRB3ADRB2ADRB1 | |
| SCHEMBL4427576 | 0.80 | ADRB3 (0.64) | ADRB3ADRB2ADRB1DRD2DRD4 | |
| SCHEMBL11672728 | 0.79 | ADRB2 (0.55) | ADRB3ADRB2ADRB1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL3227981 | 0.79 | ADRB2 (0.62) | ADRB3ADRB2ADRB1DRD2DRD1 | |
| SCHEMBL11670110 | 0.79 | ADRB2 (0.52) | ADRB3ADRB2ADRB1 | |
| Carbuterol SCHEMBL37370 | 0.79 | ADRB2 (0.58) | ADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550133-B2 | Respiratory drug condensation aerosols and methods of making and using them | ALEXZA PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |