Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.61 |
| ▸ | MTOR | P42345 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220388 | 1.00 | ADRB2 (0.61) | ADRB2MAPTTDP1KDM4EADRB1 | |
| Hydrochloric Acid SCHEMBL3227981 | 0.98 | ADRB2 (0.62) | ADRB2MAPTTDP1KDM4EADRB1 | |
| SCHEMBL13790391 | 0.95 | ADRB2 (0.62) | ADRB2MAPTTDP1KDM4EADRB1 | |
| SCHEMBL9768158 | 0.94 | ADRB2 (0.63) | ADRB2MAPTTDP1KDM4EADRB1 | |
| SCHEMBL9768151 | 0.94 | ADRB2 (0.63) | ADRB2MAPTTDP1KDM4EADRB1 | |
| SCHEMBL3503273 | 0.90 | ADRB2 (0.65) | ADRB2MAPTTDP1KDM4EADRB1 | |
| SCHEMBL3215110 | 0.90 | ADRB2 (0.65) | ADRB2MAPTTDP1KDM4EADRB1 | |
| Hydrochloric Acid SCHEMBL3207449 | 0.89 | ADRB2 (0.66) | ADRB2MAPTTDP1KDM4EADRB1 | |
| Hexoprenaline SCHEMBL121449 | 0.89 | ADRB2 (0.72) | ADRB2MAPTTDP1KDM4EADRB1 | |
| Hexoprenaline SCHEMBL32668781 | 0.89 | ADRB2 (0.72) | ADRB2MAPTTDP1KDM4EADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923101-A | Cyclic compound | 武田药品工业株式会社 | 2019-06-21 | — | — | CN | disclosed |
| CN-109862897-A | Painless, edema-free and side-effect-free injectable composition for topical fat reduction and method for preparing the same | 啊美药业 | 2019-06-07 | — | — | CN | disclosed |
| CN-105899505-B | Pyrazoles for the treatment of autoimmune disorders | 武田药品工业株式会社 | 2018-08-28 | — | — | CN | disclosed |
| US-9964552-B2 | Mass spectrometric identification and/or quantitation of catecholamines using aminopyrazoles | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2018-05-08 | — | — | US | disclosed |
| US-8506935-B2 | Respiratory drug condensation aerosols and methods of making and using them | ALEXZA PHARMACEUTICALS, INC. (US) | 2013-08-13 | — | — | US | disclosed |
| US-20090258075-A1 | Respiratory Drug Condensation Aerosols and Methods of Making and Using Them | ALEXZA PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-5047592-A | Selective hydrogenolysis process | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-4244967-A | ANTIIFLAMMATORY AND ANTIRHEUMATIC PROPERTIES | BOEHRINGER INGELHEIM GMBH (DE) | 1981-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258075-A1 | Respiratory Drug Condensation Aerosols and Methods of Making and Using Them | LTC4S, PTGER1, PTGES | ADRB2 13/4885MAPT 2548/4885TDP1 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.