Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.78 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14261172 | 0.93 | CYP24A1 (0.77) | VDRCYP24A1 | |
| SCHEMBL14416721 | 0.93 | CYP24A1 (0.77) | VDRCYP24A1 | |
| SCHEMBL12190442 | 0.93 | CYP24A1 (0.77) | VDRCYP24A1 | |
| SCHEMBL9883791 | 0.93 | CYP24A1 (0.77) | VDRCYP24A1 | |
| SCHEMBL9009939 | 0.92 | VDR (0.79) | VDRCYP24A1 | |
| SCHEMBL861063 | 0.92 | VDR (0.79) | VDRCYP24A1 | |
| SCHEMBL13665667 | 0.92 | VDR (0.79) | VDRCYP24A1 | |
| SCHEMBL19601388 | 0.92 | VDR (0.79) | VDRCYP24A1 | |
| SCHEMBL9010586 | 0.92 | VDR (0.79) | VDRCYP24A1 | |
| SCHEMBL4168336 | 0.92 | VDR (0.73) | VDRCYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541349-B2 | 2-methylene-19-nor-(23S)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone and 2-methylene-19-nor-(23R)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-06-02 | — | — | US | disclosed |