Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 11/20 | 0.56 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842642 | 0.86 | ALDH1A1 (0.55) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL29949354 | 0.86 | ALDH1A1 (0.55) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL30254122 | 0.86 | CA2 (0.57) | ERN1PLCG1GAAMAPTCDK1 | |
| SCHEMBL9149620 | 0.84 | ALDH1A1 (0.53) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL31347919 | 0.84 | ERN1 (0.55) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL31347922 | 0.84 | ERN1 (0.55) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL136274 | 0.84 | ERN1 (0.53) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL5728774 | 0.84 | ALDH1A1 (0.53) | ERN1PLCG1CDK1TRIM24TRIM33 | |
| SCHEMBL5728771 | 0.84 | PLCG1 (0.69) | ERN1PLCG1POLBCDK1TRIM24 | |
| SCHEMBL9149614 | 0.84 | PLCG1 (0.69) | ERN1PLCG1POLBCDK1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009072002-A2 | BISPHENOLS IN CANCER THERAPY | UNIVERSITY OF MANITOBA (US) | 2009-06-11 | — | — | WO | disclosed |