SCHEMBL13800142

SCHEMBL13800142

COc1cc(-c2cccc(CN(Cc3ccccc3)C3CCN(Cc4ccnc(-c5cc(OC)c(OC)c(OC)c5)c4)CC3)c2)cc(OC)c1OC

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
MAPK1 P28482 1/20 0.46
BACE1 P56817 5/20 0.46
ACHE P22303 4/20 0.46
BCHE P06276 4/20 0.46
HCRTR1 O43613 4/20 0.44
HCRTR2 O43614 4/20 0.44
DRD4 P21917 2/20 0.44
DRD2 P14416 1/20 0.44
DRD3 P35462 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
CXCR4 P61073 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4116554 0.99 HTR7 (0.46) HTR7MEN1KMT2AKDM4EALDH1A1
SCHEMBL6168618 0.96 BACE1 (0.49) HTR7MEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL4116142 0.95 BACE1 (0.48) HTR7MEN1KMT2AKDM4EALDH1A1
SCHEMBL13800151 0.91 BACE1 (0.44) HTR7MEN1KMT2AKDM4EALDH1A1
SCHEMBL13800775 0.91 HTR7 (0.46) HTR7MEN1KMT2ABACE1ACHE
Hydrochloric Acid SCHEMBL4127582 0.90 BACE1 (0.43) HTR7MEN1KMT2AKDM4EALDH1A1
Hydrochloric Acid SCHEMBL7223790 0.90 HTR7 (0.46) HTR7MEN1KMT2ABACE1ACHE
SCHEMBL6328221 0.90 HTR7 (0.46) HTR7MEN1KMT2ABACE1ACHE
SCHEMBL13800149 0.89 BACE1 (0.45) MEN1KMT2AKDM4EALDH1A1LMNA
Hydrochloric Acid SCHEMBL4132582 0.88 BACE1 (0.44) MEN1KMT2AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR KOWA CO., LTD. (JP) 2009-06-04 US disclosed
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR KOWA CO., LTD. (JP) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR EPOR, GHRHR, ARL1 HTR7 3747/4885MEN1 4312/4885KMT2A 2020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.