SCHEMBL13800577

SCHEMBL13800577

COc1cc(-c2cccc(CN(c3ccc(C)cc3)C3CCNCC3)c2)cc(OC)c1OC

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 12/20 0.48
SLC6A4 P31645 12/20 0.48
SLC6A3 Q01959 11/20 0.48
TGFBR1 P36897 2/20 0.38
ACVR1 Q04771 2/20 0.38
HTR7 P34969 1/20 0.38
MAOB P27338 1/20 0.38
ACVR1B P36896 1/20 0.37
KCNH2 Q12809 1/20 0.37
CACNA1B Q00975 1/20 0.37
TACR1 P25103 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4108594 0.99 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13800334 0.92 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13800763 0.92 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3HTR7MAOB
SCHEMBL13813567 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13813623 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3HTR7MAOB
Hydrochloric Acid SCHEMBL4132545 0.91 SLC6A2 (0.52) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13800632 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13813592 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3TGFBR1ACVR1
SCHEMBL13800650 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3HTR7MAOB
SCHEMBL13800736 0.91 SLC6A2 (0.47) SLC6A2SLC6A4SLC6A3HTR7MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR KOWA CO., LTD. (JP) 2009-06-04 US disclosed
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR KOWA CO., LTD. (JP) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR EPOR, GHRHR, ARL1 SLC6A2 4192/4885SLC6A4 3416/4885SLC6A3 3947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.