SCHEMBL13813623

SCHEMBL13813623

COc1cc(-c2cccc(CN(c3ccc(O)cc3)C3CCNCC3)c2)cc(OC)c1OC

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 11/20 0.47
SLC6A3 Q01959 11/20 0.47
SLC6A4 P31645 10/20 0.47
CACNA1B Q00975 1/20 0.40
MAOB P27338 1/20 0.39
ERN1 O75460 1/20 0.38
HTR7 P34969 1/20 0.37
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
ADRB3 P13945 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13800577 0.91 SLC6A2 (0.48) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13800334 0.91 SLC6A2 (0.52) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13800763 0.91 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13800632 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13813592 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13800736 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4MAOBHTR7
Hydrochloric Acid SCHEMBL4132545 0.90 SLC6A2 (0.52) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13800650 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
SCHEMBL13813567 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB
Hydrochloric Acid SCHEMBL4108594 0.90 SLC6A2 (0.47) SLC6A2SLC6A3SLC6A4CACNA1BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR KOWA CO., LTD. (JP) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090143430-A1 ERYTHROPOIETIN PRODUCTION ACCELERATOR EPOR, GHRHR, ARL1 SLC6A2 4192/4885SLC6A3 3947/4885SLC6A4 3416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.